Type VI secretion regulation: crosstalk and intracellular communication.

  title={Type VI secretion regulation: crosstalk and intracellular communication.},
  author={Ka Yin Leung and Bupe A. Siame and Heather Snowball and Y H Mok},
  journal={Current opinion in microbiology},
  volume={14 1},
Pathogens use type VI secretion systems (T6SSs) to transport proteins into the environment or host cells in response to external stimuli. T6SSs are tightly regulated together with other virulence determinants such as type III secretion systems, quorum sensing (QS), and flagella synthesis. Five pathogens (Salmonella enterica, Edwardsiella tarda, Aeromonas hydrophila, Vibrio cholerae, and Pseudomonas aeruginosa) are examined for crosstalk proteins (global regulators) that connect T6SSs to other… CONTINUE READING

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