Type VI collagen in extracellular, 100-nm periodic filaments and fibrils: identification by immunoelectron microscopy

@article{Bruns1986TypeVC,
  title={Type VI collagen in extracellular, 100-nm periodic filaments and fibrils: identification by immunoelectron microscopy},
  author={Romaine R. Bruns and William Press and Eva Engvall and Rupert Timpl and Jerome Gross},
  journal={The Journal of Cell Biology},
  year={1986},
  volume={103},
  pages={393 - 404}
}
Filaments and fibrils that exhibit a 100-nm axial periodicity and occur in the medium and in the deposited extracellular matrix of chicken embryo and human fibroblast cultures have been tentatively identified with type VI collagen on the basis of their similar structural characteristics (Bruns, R. R., 1984, J. Ultrastruct. Res., 89:136-145). Using indirect immunoelectron microscopy and specific monoclonal and polyclonal antibodies, we now report their positive identification with collagen VI… CONTINUE READING
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