Type Transforming Growth Factors Promote Interleukin-3 (IL-3)-Dependent Differentiation of Human Basophils But Inhibit IL-3-Dependent Differentiation of Human Eosinophils

Abstract

Basophils and eosinophils share a common differentiation pathway. Factors regulating terminal committment toward one cell type, however, have so far not been defined. Interleukin-3 (IL-3) is a potent differentiation factor for both human eosinophils and basophils. In the present study, the effects of various recombinant human (rh) growth regulators on IL… (More)

Topics

8 Figures and Tables