Type-Specific Persistence of High-Risk Human Papillomavirus Infections in the New Independent States of the former Soviet Union Cohort Study

@article{Kulmala2007TypeSpecificPO,
  title={Type-Specific Persistence of High-Risk Human Papillomavirus Infections in the New Independent States of the former Soviet Union Cohort Study},
  author={Satu-Maria A Kulmala and Irena P Shabalova and Nikolay Petrovitchev and Kari Juhani Syrj{\"a}nen and Ulf Gyllensten and Bo C Johansson and Stina M. Syrj{\"a}nen},
  journal={Cancer Epidemiology Biomarkers \& Prevention},
  year={2007},
  volume={16},
  pages={17 - 22}
}
Background: Prospective follow-up studies have recently suggested that persistent high-risk human papillomavirus (HPV) infections play a key role in the progression of CIN lesions and in the development of cervical cancer. However, data on type-specific persistence, viral integration, and the role of multiple infections are scanty. Materials and Methods: A cross-sectional/cohort study was conducted between 1998 and 2002 in three New Independent States of the former Soviet Union comprising a… 
View on AACR
cebp.aacrjournals.org
49 Citations
Highly Influential Citations
4
Background Citations
15
Methods Citations
3
Results Citations
3

49 Citations

Citation Type

Citation Type

Viral load in the natural history of human papillomavirus type 16 infection: a nested case-control study.
TLDR
Viral load of newly detected infections and changes in viral load predict persistence and progression of HPV-16 infections.
Human Papillomavirus Persistence in Young Unscreened Women, a Prospective Cohort Study
TLDR
It is shown that hr-HPV infections are more likely to persist the longer they have been present and that women with a persistent hr- HPV infection have a high risk of HSIL/CIN2+ development.
High-risk human papillomavirus associated with incident cervical intraepithelial neoplasia developing in mothers in the Finnish Family HPV Study cohort
TLDR
Baseline HR-HPV infections and their persistence precede incident CIN by several years and the risk for incident Cin increased up to 4-fold with increasing number of deliveries and decreased with history of genital warts, according to multivariate conditional logistic regression.
Host and viral factors in relation to clearance of human papillomavirus infection: A cohort study in Taiwan
TLDR
Investigation of the host and viral factors related to outcome of HPV infection in women with HPV‐positive but normal cytology and negative colposcopy found older age was associated with significantly decreased total HPV clearance and decreased type‐specific clearance in HPV‐18 and ‐53, while high viral load wasassociated with decreased total and type‐ specific clearance.
Patterns of cervical coinfection with multiple human papilloma virus types in a screening population in Denmark.
Persistence of high‐risk human papillomavirus infection in a population‐based cohort of Danish women
TLDR
To determine the type‐specific HPV persistence and risk factors for persistence of high‐risk HPV infections in a large cohort of Danish women, a population‐based prospective cohort study of women aged 20–29 years showed that use of an intrauterine device decreased the risk for persistent high‐ risk HPV infection among women with one high‐ Risk HPV type at baseline.
Dynamics of human papillomavirus serology in women followed up for 36 months after pregnancy.
TLDR
A substantial proportion of young women are seropositive for both LR- and HR-HPV types, and they frequently undergo seroconversion within 18-24 months, predicted by common covariates, and antibody decay over 3 years is rare.
Type-specific prevalence and persistence of human papillomavirus in women in the United States who are referred for typing as a component of cervical cancer screening.
A 7.5-year prospective study of longer than 18 months type-specific human papillomavirus persistence in a routine cytology-based cervical screening population of about 31 000 women in West Germany
The objective of this study was to analyse the prevalence, infection pattern, duration and outcome of long-term, type-specific, persistent human papillomavirus (HPV) infections in a routine…
Human papillomavirus (HPV) types 16, 18, 31, 45 DNA loads and HPV-16 integration in persistent and transient infections in young women
TLDR
The relationship between HPV-16 and HPV-18 DNA loads and infection clearance followed a clear dose-response pattern, after adjusting for age and number of sexual partners.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 32 REFERENCES
A prospective study showing long-term infection with human papillomavirus 16 before the development of cervical carcinoma in situ.
TLDR
Evidence of persistent and/or recurrent infection is associated with a drastically higher risk of cervical carcinoma in situ than occasional infection with HPV16, and this nested case-control study was carried out in a population-based cohort of women participating in cytological screening.
Factors predicting persistence of high-risk human papillomavirus (HPV) infections in women prospectively followed-up in three New Independent States (NIS) of the former Soviet Union.
TLDR
While several factors were related to HR-HPV persistence in univariate analysis and when adjusted for age and follow-up time as confounders, the only independent predictors in the multivariate regression model were follow- up time and HR- HPV positive PCR.
The natural history of type-specific human papillomavirus infections in female university students.
  • H. Richardson, Gail Kelsall, +5 authors E. Franco
  • Biology
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
  • 2003
TLDR
The objectives of this study were to evaluate the rate of acquisition and clearance of specific HPV types in young women and to estimate the cumulative probability of acquiring or clearing a HPV infection considering types individually or in high-risk (HR) or low- risk (LR) groups defined by oncogenic potential.
Incidence, prevalence, and clearance of type-specific human papillomavirus infections: The Young Women's Health Study.
TLDR
The natural history of type-specific human papillomavirus (HPV) infections was examined in a cohort of 331 women aged 18-35 years who self-referred for routine gynecological care, with women who had had >/=1 new male sex partner in the recent past significantly more likely to acquire a new HPV infection.
Acquisition of High-Risk Human Papillomavirus Infections and Pap Smear Abnormalities among Women in the New Independent States of the Former Soviet Union
TLDR
At the baseline the high load of a particular HR HPV type is the single most important predictor of an incident Pap smear abnormality, whereas young age and having a sexually transmitted disease predict incident HR HPV infections.
Clearance of high-risk human papillomavirus (HPV) DNA and PAP smear abnormalities in a cohort of women subjected to HPV screening in the New Independent States of the former Soviet Union (the NIS cohort study).
Epidemiology of acquisition and clearance of cervical human papillomavirus infection in women from a high-risk area for cervical cancer.
TLDR
Acquisition and clearance of cervical human papillomavirus infection were analyzed among 1425 low-income women attending a maternal and child health program in São Paulo, Brazil, and nononcogenic-type infections lasted longer among younger (<35 years old) than in older women.
Natural history of cervical human papillomavirus infection in young women: a longitudinal cohort study
Sexual Habits and Human Papillomavirus Infection Among Females in Three New Independent States of the Former Soviet Union
TLDR
The results of this study indicate that women and girls in these NIS countries are conservative in many key characteristics of “high-risk” sexual behavior, such as age at onset of sexual activity, number of partners, and casual sex partners.
Persistence and load of high‐risk HPV are predictors for development of high‐grade cervical lesions: A longitudinal French cohort study
TLDR
The incidence of cytologic abnormalities strongly depended on baseline viral load and HR‐HPV persistence and maintenance of cytological abnormalities was associated with the outcome of HR‐ HPV status.
...
1
2
3
4
...