Type-Specific Cell Line Models for Type-Specific Ovarian Cancer Research

  title={Type-Specific Cell Line Models for Type-Specific Ovarian Cancer Research},
  author={Michael S Anglesio and Kimberly C. Wiegand and Nataliya Melnyk and Christine Chow and C. Jorge E. Salamanca and Leah M Prentice and Janine Senz and Winnie Yang and Monique A. Spillman and Dawn R Cochrane and Karey Shumansky and Sohrab P. Shah and Steve E Kalloger and David G. Huntsman},
  booktitle={PloS one},
BACKGROUND OVARIAN CARCINOMAS CONSIST OF AT LEAST FIVE DISTINCT DISEASES: high-grade serous, low-grade serous, clear cell, endometrioid, and mucinous. Biomarker and molecular characterization may represent a more biologically relevant basis for grouping and treating this family of tumors, rather than site of origin. Molecular characteristics have become the new standard for clinical pathology, however development of tailored type-specific therapies is hampered by a failure of basic research to… CONTINUE READING
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