Type III neuregulin‐1 promotes oligodendrocyte myelination

@article{Taveggia2008TypeIN,
  title={Type III neuregulin‐1 promotes oligodendrocyte myelination},
  author={Carla Taveggia and Pratik Thaker and Ashley Petrylak and Gregg L. Caporaso and Arrel D. Toews and Douglas L. Falls and Steven Einheber and James L. Salzer},
  journal={Glia},
  year={2008},
  volume={56}
}
The axonal signals that regulate oligodendrocyte myelination during development of the central nervous system (CNS) have not been established. In this study, we have examined the regulation of oligodendrocyte myelination by the type III isoform of neuregulin‐1 (NRG1), a neuronal signal essential for Schwann cell differentiation and myelination. In contrast to Schwann cells, primary oligodendrocytes differentiate normally when cocultured with dorsal root ganglia (DRG) neurons deficient in type… 
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Neuregulin-1 Type III Determines the Ensheathment Fate of Axons
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