Type III group B streptococcal polysaccharide induces antibodies that cross-react with Streptococcus pneumoniae type 14.

@article{Guttormsen2002TypeIG,
  title={Type III group B streptococcal polysaccharide induces antibodies that cross-react with Streptococcus pneumoniae type 14.},
  author={H K Guttormsen and Carol J. Baker and Moon H. Nahm and Lawrence C. Paoletti and Susu M Zughaier and Morven S. Edwards and Dennis L Kasper},
  journal={Infection and immunity},
  year={2002},
  volume={70 4},
  pages={1724-38}
}
Covalent linkage of a bacterial polysaccharide to a protein greatly enhances the carbohydrate's immunogenicity and its binding to solid surfaces in immunoassays. These findings have spurred the development of glycoconjugate vaccines to prevent serious bacterial infections as well as the use of glycoconjugates as coating antigens in bioassays. We evaluated sera from women immunized with unconjugated group B streptococcal (GBS) type III (GBS III) polysaccharide (IIIPS) or with IIIPS covalently… CONTINUE READING

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