Type III collagen is essential for growth acceleration of human osteoblastic cells by ascorbic acid 2-phosphate, a long-acting vitamin C derivative.

@article{Maehata2007TypeIC,
  title={Type III collagen is essential for growth acceleration of human osteoblastic cells by ascorbic acid 2-phosphate, a long-acting vitamin C derivative.},
  author={Yojiro Maehata and Shinji Takamizawa and Shigeyuki Ozawa and Kazuhito Izukuri and Yasumasa Kato and Sadao Sato and M Lee and Akinori Kimura and Ryu-ichiro Hata},
  journal={Matrix biology : journal of the International Society for Matrix Biology},
  year={2007},
  volume={26 5},
  pages={371-81}
}
Collagen has been reported to be essential for the proliferation of various kinds of cells including human osteoblastic cells [Takamizawa, S., Maehata, Y., Imai, K., Senoo, H., Sato, S., Hata, R., 2004. Effects of ascorbic acid and ascorbic acid 2-phosphate, a long-acting vitamin C derivative, on the proliferation and differentiation of human osteoblast-like cells. Cell Biol. Int. 28, 255-265], but the type(s) of collagen responsible for growth regulation is not known. Presently we found that… CONTINUE READING

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