Type III Protein Secretion Systems in Bacterial Pathogens of Animals and Plants

@article{Hueck1998TypeIP,
  title={Type III Protein Secretion Systems in Bacterial Pathogens of Animals and Plants},
  author={Christoph J. Hueck},
  journal={Microbiology and Molecular Biology Reviews},
  year={1998},
  volume={62},
  pages={379 - 433}
}
  • C. Hueck
  • Published 1 June 1998
  • Biology
  • Microbiology and Molecular Biology Reviews
SUMMARY Various gram-negative animal and plant pathogens use a novel, sec-independent protein secretion system as a basic virulence mechanism. It is becoming increasingly clear that these so-called type III secretion systems inject (translocate) proteins into the cytosol of eukaryotic cells, where the translocated proteins facilitate bacterial pathogenesis by specifically interfering with host cell signal transduction and other cellular processes. Accordingly, some type III secretion systems… 
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