Type II toxin: antitoxin systems. More than small selfish entities?

  title={Type II toxin: antitoxin systems. More than small selfish entities?},
  author={A. Rocker and A. Meinhart},
  journal={Current Genetics},
  pages={287 - 290}
  • A. Rocker, A. Meinhart
  • Published 2015
  • Biology, Medicine
  • Current Genetics
  • Toxin–antitoxin (TA) modules regulate metabolism and viability of bacteria and archaea. In type II TA systems these functions are generally thought to be performed by two small proteins. However, evidence is increasing that the toxins are much more diverse and can form multi-domain proteins. Recently, we published a novel type II TA system in which toxin and antitoxin are covalently linked into a single polypeptide chain. In this review we summarize the current knowledge on these elongated… CONTINUE READING

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