Type II ground-glass hepatocytes as a marker of hepatocellular carcinoma in chronic hepatitis B.

@article{Mathai2013TypeIG,
  title={Type II ground-glass hepatocytes as a marker of hepatocellular carcinoma in chronic hepatitis B.},
  author={Alka Mary Mathai and Jacob Alexander and Fu Hsuan Kuo and Michael S. Torbenson and Paul E. Swanson and Matthew M Yeh},
  journal={Human pathology},
  year={2013},
  volume={44 8},
  pages={
          1665-71
        }
}

• Alka Mary Mathai, Jacob Alexander, +3 authors Matthew M Yeh
• Published 2013 in Human pathology
• DOI:10.1016/j.humpath.2013.01.020

Ground-glass hepatocytes are seen in chronic hepatitis B virus (HBV) infection and are known to harbor pre-S mutants, which are implicated in the pathogenesis of hepatocellular carcinoma (HCC). However, the association between ground-glass hepatocytes and HCC has yet to be clearly elucidated. The aim in the present study was to investigate the association of ground-glass hepatocytes with (1) the histologic characteristics of HBV-related HCC and (2) the grade of inflammation, stage of fibrosis… CONTINUE READING

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