Type I interferon-mediated autoinflammation and autoimmunity.

Abstract

The monogenic type I interferonopathies comprise a heterogenous group of disorders of the innate immune system associated with constitutive activation of antiviral type I interferon (IFN). Despite a remarkable phenotypic diversity, type I interferonopathies are commonly characterized by autoinflammation and varying degrees of autoimmunity or… (More)
DOI: 10.1016/j.coi.2017.09.003

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