Type I hereditary punctate keratoderma.

  title={Type I hereditary punctate keratoderma.},
  author={Arash Kimyia Asadi},
  journal={Dermatology online journal},
  volume={9 4},
A 75-year-old man with a history of prostatic carcinoma and atypical fibroxanthoma reports a long-standing history of 1-2 mm depressed, hyperkeratotic papules on the palms. His mother suffered a similar condition. Histologically, the papules demonstrated hyperkeratosis, without columns of parakeratosis. A diagnosis of type I hereditary punctate keratoderma (Buschke-Fisher-Brauer disease) was made. This condition, which is classified as one of the three hereditary forms of punctate palmoplantar… CONTINUE READING