Type I and II endometrial cancers: have they different risk factors?

  title={Type I and II endometrial cancers: have they different risk factors?},
  author={Veronica Wendy Setiawan and Hannah Yang and Malcolm C. Pike and Susan E. McCann and Herbert Yu and Y. P. Xiang and Alicja Wolk and Nicolas Wentzensen and Noel S Weiss and Penelope M Webb and Piet A van den Brandt and K. K. B. T. Van de Vijver and Pamela J. Thompson and Brian L. Strom and Amanda B Spurdle and Robert A Soslow and Xiao-ou Shu and Catherine Schairer and Carlotta Sacerdote and Thomas Rohan and Kim Robien and Harvey A. Risch and Fulvio Ricceri and Timothy R. Rebbeck and Radhai Rastogi and Jennifer Prescott and Silvia Polidoro and Yikyung Park and Sara H. Olson and Kirsten B Moysich and Anthony B. Miller and Marjorie L McCullough and Rayna Kim Matsuno and Anthony M. Magliocco and Galina Lurie and Lingeng Lu and Jolanta Lissowska and Xiaolin Liang and James V Lacey and Laurence N. Kolonel and Brian E. Henderson and Susan E. Hankinson and Niclas H{\aa}kansson and Marc T. Goodman and Mia M Gaudet and Montserrat Garc{\'i}a-Closas and Christine M Friedenreich and Jo L Freudenheim and Jennifer K Doherty and Immaculata De Vivo and Kerry S Courneya and Linda Sue Cook and Chu Chen and James R. Cerhan and Hui Cai and Louise A Brinton and Leslie Bernstein and Kristin E. Anderson and Hoda Anton-Culver and Leo J Schouten and Pamela L. Horn-Ross},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  volume={31 20},
PURPOSE Endometrial cancers have long been divided into estrogen-dependent type I and the less common clinically aggressive estrogen-independent type II. Little is known about risk factors for type II tumors because most studies lack sufficient cases to study these much less common tumors separately. We examined whether so-called classical endometrial cancer risk factors also influence the risk of type II tumors. PATIENTS AND METHODS Individual-level data from 10 cohort and 14 case-control… CONTINUE READING
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