Type I PIPK-α regulates directed cell migration by modulating Rac1 plasma membrane targeting and activation

Abstract

The Rockefeller University Press $30.00 J. Cell Biol. Vol. 190 No. 2 247–262 www.jcb.org/cgi/doi/10.1083/jcb.200911110 JCB 247 Correspondence to Jeannette Kunz: jkunz@bcm.tmc.edu A.C. Daquinag’s present address is The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Disease, University of Texas Health Science Center at Houston, Houston, TX 77030. Abbreviations used in this paper: FN, fibronectin; GEF, GTP exchange factor; PH, pleckstrin homology; PI4,5P2, phosphatidylinositol-4,5-bisphosphate; PIPKI, type I phosphatidylinositol-4-phosphate 5-kinase; RhoGDI, Rho guanine nucleotide dissociation inhibitor. Introduction

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@inproceedings{Chao2010TypeIP, title={Type I PIPK-α regulates directed cell migration by modulating Rac1 plasma membrane targeting and activation}, author={W Chao and Alexes C. Daquinag and Felicity J Ashcroft and Jeannette Kunz}, year={2010} }