Type I IFN-mediated protection of macrophages and dendritic cells secures control of murine coronavirus infection.

@article{CervantesBarragan2009TypeII,
  title={Type I IFN-mediated protection of macrophages and dendritic cells secures control of murine coronavirus infection.},
  author={Luisa Cervantes-Barragan and Ulrich Kalinke and Roland Z{\"u}st and Martin K{\"o}nig and Boris Reizis and Constantino L{\'o}pez-Mac{\'i}as and Volker Thiel and Burkhard Ludewig},
  journal={Journal of immunology},
  year={2009},
  volume={182 2},
  pages={
          1099-106
        }
}
The swift production of type I IFNs is one of the fundamental aspects of innate immune responses against viruses. Plasmacytoid dendritic cell-derived type I IFNs are of prime importance for the initial control of highly cytopathic viruses such as the mouse hepatitis virus (MHV). The aim of this study was to determine the major target cell populations of this first wave of type I IFNs. Generation of bone marrow-chimeric mice expressing the type I IFN receptor (IFNAR) on either hemopoietic or non… CONTINUE READING

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Identification of coronavirus non-structural protein 1 as a major pathogenicity factor-implications for the rational design of live attenuated coronavirus vaccines

R. Züst, L. Cervantes-Barragan, +4 authors V. Thiel
  • PLoS Pathog
  • 2007
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Type I interferons are essential in controlling neurotropic coronavirus infection irrespective of functional CD8 T cells

D. D. Ireland, S. A. Stohlman, D. R. Hinton, R. Atkinson, C. C. Bergmann
  • J. Virol
  • 2008
VIEW 1 EXCERPT