Type I Glanzmann's thrombasthenia in a Great Pyrenees dog.

  title={Type I Glanzmann's thrombasthenia in a Great Pyrenees dog.},
  author={Mary K. Boudreaux and Ketil Kvam and Allen R. Dillon and Candace Bourne and Melanie Scott and Kenneth A. Schwartz and Maria A Toivio-Kinnucan},
  journal={Veterinary pathology},
  volume={33 5},
An 8-month-old female Great Pyrenees dog with chronic epistaxis and a history of gingival bleeding during shedding of deciduous teeth was evaluated for platelet function. Platelet morphology was normal at both the light and electron microscopic level. Platelet number and mean platelet volume were also normal. Platelet aggregation responses to adenosine diphosphate, collagen, platelet activating factor, and thrombin were markedly reduced, although shape change responses were normal. Clot… CONTINUE READING