Type 5 adenylyl cyclase plays a major role in stabilizing heart rate in response to microgravity induced by parabolic flight.

Abstract

It is well known that autonomic nervous activity is altered under microgravity, leading to disturbed regulation of cardiac function, such as heart rate. Autonomic regulation of the heart is mostly determined by beta-adrenergic receptors/cAMP signal, which is produced by adenylyl cyclase, in cardiac myocytes. To examine a hypothesis that a major cardiac… (More)
DOI: 10.1152/japplphysiol.01166.2007

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Cite this paper

@article{Okumura2008Type5A, title={Type 5 adenylyl cyclase plays a major role in stabilizing heart rate in response to microgravity induced by parabolic flight.}, author={Satoshi Okumura and Takashi Tsunematsu and Yunzhe Bai and Qibin Jiao and Shinji Ono and Sayaka T Suzuki and Reiko Kurotani and Motohiko Sato and Susumu Minamisawa and Satoshi Umemura and Yoshihiro Ishikawa}, journal={Journal of applied physiology}, year={2008}, volume={105 1}, pages={173-9} }