Type 2B vWD: the varied clinical manifestations in two kindreds.

@article{Mathew2003Type2V,
  title={Type 2B vWD: the varied clinical manifestations in two kindreds.},
  author={Prasad Mathew and Anne Greist and Jennifer A Maahs and Erik Lichtenberg and Amy D Shapiro},
  journal={Haemophilia : the official journal of the World Federation of Hemophilia},
  year={2003},
  volume={9 1},
  pages={137-44}
}
Type 2B von Willebrand's disease (vWD) is associated with spontaneous binding of large von Willebrand factor (vWF) multimers to platelets in vivo, followed by clearance of both the large multimers and platelets resulting in thrombocytopenia, which may be intermittent, mild to severe, and may be exacerbated by stress such as infection or pregnancy. We report our experience in two kindreds (49 caucasian individuals) with type 2B vWD and discuss their varied clinical manifestations. The largest… CONTINUE READING

Similar Papers

Loading similar papers…