Type 2 secretion promotes enterohemorrhagic Escherichia coli adherence and intestinal colonization.

@article{Ho2008Type2S,
  title={Type 2 secretion promotes enterohemorrhagic Escherichia coli adherence and intestinal colonization.},
  author={Theresa Deland Ho and Brigid M. Davis and Jennifer M. Ritchie and Matthew K Waldor},
  journal={Infection and immunity},
  year={2008},
  volume={76 5},
  pages={1858-65}
}
Enterohemorrhagic Escherichia coli (EHEC) is a noninvasive food-borne pathogen that colonizes the distal ileum and colon. Proteins encoded in the EHEC locus of enterocyte effacement (LEE) pathogenicity island are known to contribute to this pathogen's adherence to epithelial cells and intestinal colonization. The role of non-LEE-encoded proteins in these processes is not as clear. We found that the Z2053 gene (designated adfO here), a gene located in a cryptic EHEC prophage, exhibits similarity… CONTINUE READING

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