Type 2 diabetes is negatively associated with Alzheimer's disease neuropathology.

@article{Beeri2005Type2D,
  title={Type 2 diabetes is negatively associated with Alzheimer's disease neuropathology.},
  author={Michal Schnaider Beeri and Jeremy M. Silverman and KennethL. Davis and DeborahB. Marin and Hillel Z Grossman and James Schmeidler and Dushyant P. Purohit and DanielP. Perl and Michael Davidson and RichardC. Mohs and Vahram Haroutunian},
  journal={The journals of gerontology. Series A, Biological sciences and medical sciences},
  year={2005},
  volume={60 4},
  pages={
          471-5
        }
}
BACKGROUND In cross-sectional and longitudinal studies, type 2 diabetes has been positively associated with the risk of Alzheimer's disease (AD). The present descriptive study compared diabetic and nondiabetic subjects on the severity of neuritic plaques and neurofibrillary tangles (NFTs) in the cerebral cortex and in the hippocampus. METHODS The study included specimens from 385 consecutive autopsies of residents of a nursing home (15.8% diabetics). Mean age at death = 84 years [standard… CONTINUE READING

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