Type 2 diabetes in youth: are there racial differences in β-cell responsiveness relative to insulin sensitivity?

@article{Bacha2012Type2D,
  title={Type 2 diabetes in youth: are there racial differences in β-cell responsiveness relative to insulin sensitivity?},
  author={Fida Bacha and Neslihan Gungor and Sojung Lee and Silva Arslanian},
  journal={Pediatric diabetes},
  year={2012},
  volume={13 3},
  pages={259-65}
}
OBJECTIVE Non-diabetic African American (AA) youth have an upregulated insulin secretion relative to insulin sensitivity (IS) compared with their American White (AW) peers. We investigated if similar racial differences exist in youth with T2DM. RESEARCH DESIGN AND METHODS Fourteen AAs and 14 AWs T2DM adolescents underwent evaluation of IS and clearance (hyperinsulinemic-euglycemic clamp), first- and second-phase insulin and C-peptide secretion (hyperglycemic clamp); body composition (DEXA… CONTINUE READING
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in obese youth : insulin sensitivity and secretion in islet cell antibody - negative versus - positive patients

  • F Bacha, R Saad, N Gungor, S Arslanian
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