Type 2 diabetes as a redox disease

@article{Watson2014Type2D,
  title={Type 2 diabetes as a redox disease},
  author={James D. Watson},
  journal={The Lancet},
  year={2014},
  volume={383},
  pages={841-843}
}
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Despite its strong association with type 2 diabetes, however, hyperglycemia is not the disease per se, it is important to ask what other variables besides glucose are relevant to the disorder.
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Current strategies of prevention and pharmacologic management of T2D were critically reexamined with particular emphasis on their potential redox‐related rationale.
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The objective of the present study was to investigate the relationship between plasma interleukin‐22 (IL‐22) levels and prediabetes or type 2 diabetes, and search the relevance between plasma
Membrane Flexibility and Cellular Energy Management in Type 2 Diabetes, Gestational Diabetes, and Obesity
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It is now clear that increasing the USI with longterm interventions in the form of aerobic exercise and caloric restriction can contribute to the prevention or postponement of the onset of T2DM, gestational diabetes, and prediabetic obesity.
Carotenoids in the treatment of diabetes mellitus and its complications: A mechanistic review.
Oxidative Stress and Cardiovascular Risk in Type 1 Diabetes Mellitus: Insights From the DCCT/EDIC Study
  • W. Tang, P. McGee, +549 authors K. McVary
  • Medicine
    Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
  • 2018
TLDR
Higher paraoxonase activity, reflective of antioxidant activity, and 2,3 dinor‐8 iso prostaglandin F2α, an oxidative marker, were significantly associated with lower risk of cardiovascular disease, but these biomarkers did not change over time with intensification of glycemic control.
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