Type 2 Diabetes Is Associated with Altered NF-κB DNA Binding Activity, JNK Phosphorylation, and AMPK Phosphorylation in Skeletal Muscle after LPS

@inproceedings{Andreasen2011Type2D,
  title={Type 2 Diabetes Is Associated with Altered NF-κB DNA Binding Activity, JNK Phosphorylation, and AMPK Phosphorylation in Skeletal Muscle after LPS},
  author={Anne Sofie Andreasen and Meghan K. Kelly and Ronan Martin Griffin Berg and Kirsten M{\o}ller and Bente Klarlund Pedersen},
  booktitle={PloS one},
  year={2011}
}
UNLABELLED Systemic inflammation is often associated with impaired glucose metabolism. We therefore studied the activation of inflammatory pathway intermediates that interfere with glucose uptake during systemic inflammation by applying a standardised inflammatory stimulus in vivo. After ethical approval, informed consent and a thorough physical examination, 10 patients with type 2 diabetes and 10 participants with normal glucose tolerance (NGT) were given an intravenous bolus of E. coli… CONTINUE READING
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