Type 1 error and power of the linear trend test in proportions under the National Toxicology Program's modified pathology protocol.

  • Claude Portier
  • Published 1986 in
    Fundamental and applied toxicology : official…

Abstract

This paper investigates the relationship between the probability of detecting a statistically significant linear trend in the proportion of animals observed to have tumors for the modified pathology protocol currently being employed by The National Toxicology Program. We considered over 300 possible dose-response relationships and tested at 5% and 1… (More)

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