Type 1 diabetes mellitus: effective insulin strategies with less hypoglycemia.

@article{Bolli2004Type1D,
  title={Type 1 diabetes mellitus: effective insulin strategies with less hypoglycemia.},
  author={Geremia B Bolli},
  journal={Postgraduate medicine},
  year={2004},
  volume={116 5 Suppl Exploring},
  pages={13-20}
}
Stringent glycemic control is important for preventing the development or progression of complications in type 1 diabetes. This goal may best be achieved by intensive insulin replacement therapy that closely follows the physiologic patterns of secretion observed in patients without diabetes. Premixed insulin formulations of human regular and NPH insulin are commonly used to control blood glucose levels throughout the day, but because these preparations do not mimic the physiologic profile of… CONTINUE READING