Type 1 diabetes: virus infection or autoimmune disease?

@article{Fairweather2002Type1D,
  title={Type 1 diabetes: virus infection or autoimmune disease?},
  author={DeLisa Fairweather and Noel R. Rose},
  journal={Nature Immunology},
  year={2002},
  volume={3},
  pages={338-340}
}
What does Coxsackie virus have to do with diabetes? Evidence is emerging that insulin-producing β cells are highly susceptible to acute infection by Coxsackie virus if their production of interferon is inhibited, resulting in diabetes. 
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Results show that diabetes induced by Coxsackie virus infection is a direct result of local infection leading to inflammation, tissue damage, and the release of sequestered islet antigen resulting in the re-stimulation of resting autoreactive T cells, further indicating that the is let antigen sensitization is an indirect consequence of the viral infection.
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