Ty1 sequence with enhancer and mating-type-dependent regulatory activities.

  title={Ty1 sequence with enhancer and mating-type-dependent regulatory activities.},
  author={Beverly Errede and Mahshid Company and Clyde A. Hutchison},
  journal={Molecular and cellular biology},
  volume={7 1},
Some insertion mutations in Saccharomyces cerevisiae activate the expression of adjacent structural genes. The CYC7-H2 mutation is a Ty1 insertion 5' to the iso-2-cytochrome c coding region of CYC7. The Ty1 insertion causes a 20-fold increase in CYC7 expression in a and alpha haploid cell types of S. cerevisiae. This activation is repressed in the a/alpha diploid cell type. Previous computer analysis of the CYC7-H2 Ty1 activator region identified two related sequences with homology both to… CONTINUE READING
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