Ty element transposition: Reverse transcriptase and virus-like particles

@article{Garfinkel1985TyET,
  title={Ty element transposition: Reverse transcriptase and virus-like particles},
  author={David J Garfinkel and Jef D. Boeke and Gerald R. Fink},
  journal={Cell},
  year={1985},
  volume={42},
  pages={507-517}
}
We have found reverse transcriptase activity and virus-like particles only in yeast cells that contain a galactose-promoted Ty element induced on galactose. The cofractionation of reverse transcriptase, genomic-length Ty RNA, and a Ty-specified protein antigen in a particulate fraction and the ability of this complex to synthesize specifically a product that is homologous to the entire Ty suggest that reverse transcription of Ty RNA takes place in the particle. The absence of appreciable levels… Expand
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