Two years of replacement therapy in adults with growth hormone deficiency.

  title={Two years of replacement therapy in adults with growth hormone deficiency.},
  author={Johan A. Verhelst and Roger Abs and M V Vandeweghe and J Mockel and J. J. Legros and Georges Copinschi and Cornelia Mahler and Birgitte Velkeniers and Luc Vanhaelst and Adriaan C. van Aelst and D De Rijdt and Achile Stevenaert and Albert Beckers},
  journal={Clinical endocrinology},
  volume={47 4},
OBJECTIVES Although several studies have shown beneficial short-term effects of recombinant human growth hormone (rhGH) therapy in adult GH deficient (GHD) patients, few data are available on large groups of patients treated for more than one year. In addition, the optimal dose of rhGH for each patient and the baseline parameters that predict which patients will benefit most from therapy or will have adverse events are not entirely elucidated. DESIGN 148 adult GHD patients were enrolled in a… CONTINUE READING


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