Two-way communications between ubiquitin-like modifiers and DNA

  title={Two-way communications between ubiquitin-like modifiers and DNA},
  author={Helle D Ulrich},
  journal={Nature Structural &Molecular Biology},
Many aspects of nucleic acid metabolism, such as DNA replication, repair and transcription, are regulated by the post-translational modifiers ubiquitin and SUMO. Not surprisingly, DNA itself plays an integral part in determining the modification of most chromatin-associated targets. Conversely, ubiquitination or SUMOylation of a protein can impinge on its DNA-binding properties. This review describes mechanistic principles governing the mutual interactions between DNA and ubiquitin or SUMO. 
Highly Cited
This paper has 364 citations. REVIEW CITATIONS
Recent Discussions
This paper has been referenced on Twitter 2 times over the past 90 days. VIEW TWEETS

From This Paper

Figures, tables, and topics from this paper.


Publications citing this paper.
Showing 1-10 of 17 extracted citations

365 Citations

Citations per Year
Semantic Scholar estimates that this publication has 365 citations based on the available data.

See our FAQ for additional information.


Publications referenced by this paper.
Showing 1-10 of 141 references

Similar Papers

Loading similar papers…