Two-way communications between ubiquitin-like modifiers and DNA

@article{Ulrich2014TwowayCB,
  title={Two-way communications between ubiquitin-like modifiers and DNA},
  author={Helle D Ulrich},
  journal={Nature Structural &Molecular Biology},
  year={2014},
  volume={21},
  pages={317-324}
}
Many aspects of nucleic acid metabolism, such as DNA replication, repair and transcription, are regulated by the post-translational modifiers ubiquitin and SUMO. Not surprisingly, DNA itself plays an integral part in determining the modification of most chromatin-associated targets. Conversely, ubiquitination or SUMOylation of a protein can impinge on its DNA-binding properties. This review describes mechanistic principles governing the mutual interactions between DNA and ubiquitin or SUMO. 
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