Two viral kinases are required for sustained long distance axon transport of a neuroinvasive herpesvirus.

@article{Coller2008TwoVK,
  title={Two viral kinases are required for sustained long distance axon transport of a neuroinvasive herpesvirus.},
  author={Kelly Elizabeth Coller and Gregory A Smith},
  journal={Traffic},
  year={2008},
  volume={9 9},
  pages={1458-70}
}
Axonal transport is essential for the successful establishment of neuroinvasive herpesvirus infections in peripheral ganglia (retrograde transport) and the subsequent spread to exposed body surfaces following reactivation from latency (anterograde transport). We examined two components of pseudorabies virus (US3 and UL13), both of which are protein kinases, as potential regulators of axon transport. Following replication of mutant viruses lacking kinase activity, newly assembled capsids… CONTINUE READING