Two tyrosine hydroxylase genes in teleosts.

  title={Two tyrosine hydroxylase genes in teleosts.},
  author={Judith Candy and Chris Collet},
  journal={Biochimica et biophysica acta},
  volume={1727 1},
We report the finding of two non-allelic genes encoding tyrosine hydroxylase (TH) from the diploid teleost barramundi Lates calcarifer. Barramundi TH1 is the homologue of the higher vertebrate TH genes and encodes a protein of 489 amino acids that shares 90% sequence identity to the THs of other teleost species. A second non-allelic tyrosine hydroxylase gene (TH2) encodes a protein of 472 amino acids and shares 62% identity with TH1 and the vertebrate THs. TH1 mRNA is found in the brain and… CONTINUE READING
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