Two types of high voltage-activated calcium channels in SH-SY5Y human neuroblastoma cells.

@article{Reuveny1993TwoTO,
  title={Two types of high voltage-activated calcium channels in SH-SY5Y human neuroblastoma cells.},
  author={Eitan Reuveny and Toshio Narahashi},
  journal={Brain research},
  year={1993},
  volume={603 1},
  pages={64-73}
}
Voltage-activated calcium channel currents were recorded from differentiated human neuroblastoma cells. SK-N-SH-SY5Y (SH-SY5Y) line, using patch-clamp techniques. Experimental solutions were designed to suppress sodium and potassium channel currents, and barium ions were used as the charge carrier. Two distinct types of calcium channel currents (N- and L-like) were identified based on their time-dependent inactivation, pharmacology and single-channel conductances. N- and L-like calcium channel… CONTINUE READING

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