Two topical carbonic anhydrase inhibitors sezolamide and dorzolamide in Gelrite vehicle: A multiple-dose efficacy study

@article{Gunning2004TwoTC,
  title={Two topical carbonic anhydrase inhibitors sezolamide and dorzolamide in Gelrite vehicle: A multiple-dose efficacy study},
  author={F. Gunning and E. Greve and A. Bron and J. Bosc and J. Royer and J. George and P. Lesure and D. Sirbat},
  journal={Graefe's Archive for Clinical and Experimental Ophthalmology},
  year={2004},
  volume={231},
  pages={384-388}
}
The ocular hypotensive activities of the two potent topical carbonic anhydrase inhibitors sezolamide (previously known as MK-417) and dorzolamide (previously known as MK-507 and L-671,152) were compared formulated in Gelrite vehicle, a novel ophthalmic drug delivery system. This was a four-center, double-blind, randomized, placebo-controlled, parallel study in 73 patients with a diagnosis of bilateral primary open-angle glaucoma or ocular hypertension and a morning intraocular pressure (IOP) of… Expand
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