Two survivor pathways that allow growth in the absence of telomerase are generated by distinct telomere recombination events.

@article{Chen2001TwoSP,
  title={Two survivor pathways that allow growth in the absence of telomerase are generated by distinct telomere recombination events.},
  author={Qian Chen and A Ijpma and Carol W Greider},
  journal={Molecular and cellular biology},
  year={2001},
  volume={21 5},
  pages={1819-27}
}
Yeast cells can survive in the absence of telomerase RNA, TLC1, by recombination-mediated telomere elongation. Two types of survivors, type I and type II, can be distinguished by their characteristic telomere patterns. RAD52 is essential for the generation of both types of survivors. Deletion of both RAD50 and RAD51 produces a phenotype similar to that produced by deletion of RAD52. Here we examined the effects of the RAD50 and the RAD51 epistasis groups as well as the RAD52 homologue, RAD59… CONTINUE READING
Highly Influential
This paper has highly influenced 14 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.
93 Extracted Citations
0 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 93 extracted citations

Similar Papers

Loading similar papers…