Two structures of the catalytic domain of phosphorylase kinase: an active protein kinase complexed with substrate analogue and product.

@article{Owen1995TwoSO,
  title={Two structures of the catalytic domain of phosphorylase kinase: an active protein kinase complexed with substrate analogue and product.},
  author={David R. Owen and Mark E. Noble and Elspeth F. Garman and Anastassios C Papageorgiou and Louise N. Johnson},
  journal={Structure},
  year={1995},
  volume={3 5},
  pages={467-82}
}
BACKGROUND Control of intracellular events by protein phosphorylation is promoted by specific protein kinases. All the known protein kinase possess a common structure that defines a catalytically competent entity termed the 'kinase catalytic core'. Within this common structural framework each kinase displays its own unique substrate specificity, and a regulatory mechanism that may be modulated by association with other proteins. Structural studies of phosphorylase kinase (Phk), the major… CONTINUE READING
36 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 36 extracted citations

Similar Papers

Loading similar papers…