Two-stage transformation systems for normalization of reference distributions evaluated.

@article{Linnet1987TwostageTS,
  title={Two-stage transformation systems for normalization of reference distributions evaluated.},
  author={Kristian Linnet},
  journal={Clinical chemistry},
  year={1987},
  volume={33 3},
  pages={381-6}
}
In two-stage transformation systems for normalization of reference distributions, the asymmetry is first corrected, and any deviation of kurtosis is then adjusted. The simulation studies reported here show that these systems have previously been assessed too optimistically because the sample variation of the transformation parameters was neglected. Applying a goodness-of-fit test to transformed values shows that one should accept gaussianity only for p-values greater than 0.15 instead of those… CONTINUE READING