Two-stage prediction of the effects of imidazolium and pyridinium ionic liquid mixtures on luciferase.

@article{Ge2014TwostagePO,
  title={Two-stage prediction of the effects of imidazolium and pyridinium ionic liquid mixtures on luciferase.},
  author={Hui-Lin Ge and Shushen Liu and Bing-Xia Su and Xiang-Wei Zhu},
  journal={Molecules},
  year={2014},
  volume={19 5},
  pages={6877-90}
}
The predicted toxicity of mixtures of imidazolium and pyridinium ionic liquids (ILs) in the ratios of their EC50, EC10, and NOEC (no observed effect concentration) were compared to the observed toxicity of these mixtures on luciferase. The toxicities of EC50 ratio mixture can be effectively predicted by two-stage prediction (TSP) method, but were overestimated by the concentration addition (CA) model and underestimated by the independent action (IA) model. The toxicities of EC10 ratio mixtures… CONTINUE READING

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