Two-stage batch process for the production of ajmalicine by Catharanthus roseus: The link between growth and production stage.

@article{Schlatmann1995TwostageBP,
  title={Two-stage batch process for the production of ajmalicine by Catharanthus roseus: The link between growth and production stage.},
  author={Jurriaan E. Schlatmann and Paulo Roberto H Moreno and Montserrat Sell{\'e}s and Jacobus L Vinke and H J.G. ten Hoopen and Robert Verpoorte and Joseph J. Heijnen},
  journal={Biotechnology and bioengineering},
  year={1995},
  volume={47 1},
  pages={53-9}
}
The link between the growth stage and the production stage in a two-stage batch process was investigated using (filtered) inocula from different periods of the stationary phase of the growth cycle. In the production stage, ajmalicine production by Catharanthus roseus in a 3-L stirred tank reactor was induced with a high glucose concentration (80 g/L… CONTINUE READING

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