Two-stage association study to identify the genetic susceptibility of a novel common variant of rs2075290 in ZPR1 to type 2 diabetes

@inproceedings{Guan2016TwostageAS,
  title={Two-stage association study to identify the genetic susceptibility of a novel common variant of rs2075290 in ZPR1 to type 2 diabetes},
  author={Fanglin Guan and Yu Ming Niu and Tianxiao Zhang and Songfang Liu and Miaozhang Zhu and Ting Qi and Jia Chun Feng and Hong Zuo and Guohong Li and Xufeng Liu and Shujin Wang},
  booktitle={Scientific reports},
  year={2016}
}
The SNP of rs964184 in ZPR1 has recently been associated with type 2 diabetes mellitus (T2DM) in Japanese individuals. To comprehensively investigate the association of common variants in ZPR1 with T2DM in Han Chinese individuals, we designed a two-stage case-control study of 3,505 T2DM patients and 6,911 unrelated healthy Han Chinese individuals. A total of 24 single nucleotide polymorphisms (SNPs) were genotyped, and single-SNP association, imputation and gender-specific association analyses… CONTINUE READING
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Association of a genetic variant of the ZPR1 zinc finger gene with type 2 diabetes mellitus

F Tokoro
Biomed Rep • 2015

Association of the variants in the BUD13-ZNF259 genes and the risk of hyperlipidaemia

Aung, H L.
J Cell Mol Med • 2014

Genome-wide association study identifies three novel loci for type 2 diabetes

K Hara
Hum Mol Genet • 2014

Prevalence and control of diabetes

Y Xu
in Chinese adults • 2013

Prevalence and control of diabetes in Chinese adults

Y. Xu
JAMA • 2013

Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians

Cho, S Y.
Nat Genet • 2012

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