Two single nucleotide polymorphisms in the myostatin (GDF8) gene have significant association with muscle depth of commercial Charollais sheep.

@article{Hadjipavlou2008TwoSN,
  title={Two single nucleotide polymorphisms in the myostatin (GDF8) gene have significant association with muscle depth of commercial Charollais sheep.},
  author={Georgia Hadjipavlou and Oswald Matika and Alex Clop and Stephen Christopher Bishop},
  journal={Animal genetics},
  year={2008},
  volume={39 4},
  pages={
          346-53
        }
}
To assess whether the same mutation(s) were responsible for similar phenotypes attributed to ovine chromosome 2 (OAR2) quantitative trait loci (QTL) in different sheep breeds, Suffolk, Texel and Charollais rams from British commercial flocks were genotyped for two single nucleotide polymorphisms (SNPs) located in the myostatin (GDF8) region of OAR2, previously detected in progeny of Belgian Texel rams exhibiting muscular hypertrophy. The first SNP (g.-2449G>C) was located upstream from the… CONTINUE READING

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