Two-sided Effect of Steroids on Interferon in Tissue Culture

@article{Maeyer1963TwosidedEO,
  title={Two-sided Effect of Steroids on Interferon in Tissue Culture},
  author={Edward De Maeyer and J. DE MAEYER},
  journal={Nature},
  year={1963},
  volume={197},
  pages={724-725}
}
IN the course of an investigation of interferon production in a line of rat tumour cells (DE7R cells), infected with Sindbis virus Δ′,17α-methyltestosterone (‘Dianabol’, Ciba), an androgenic steroid known to increase protein synthesis in rats1 was added to the virus-cell system, in the hope of obtaining higher interferon yields. The effect of ‘Cortisol’ was… CONTINUE READING