Two separate domains in the golli myelin basic proteins are responsible for nuclear targeting and process extension in transfected cells.

@article{Reyes2002TwoSD,
  title={Two separate domains in the golli myelin basic proteins are responsible for nuclear targeting and process extension in transfected cells.},
  author={Samuel D. Reyes and Anthony T. Campagnoni},
  journal={Journal of neuroscience research},
  year={2002},
  volume={69 5},
  pages={587-96}
}
The golli products of the myelin basic protein (MBP) gene are expressed in neurons and oligodendrocytes (OLs). In certain neuronal populations, golli proteins undergo translocation between the nucleus and cytoplasm/processes during development. The proteins consist of two domains, a golli domain of 133 amino acids and an MBP domain of variable length. One objective of this study was to identify the sequences responsible for nuclear targeting. Site-directed mutagenesis and deletion analyses were… CONTINUE READING

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