Two regions responsible for the actin binding of p57, a mammalian coronin family actin-binding protein.

@article{Oku2003TwoRR,
  title={Two regions responsible for the actin binding of p57, a mammalian coronin family actin-binding protein.},
  author={Teruaki Oku and Saotomo Itoh and Masamitsu Okano and Akiko Suzuki and Kensuke Suzuki and Shizuo Nakajin and Tsutomu Tsuji and William M Nauseef and Satoshi Toyoshima},
  journal={Biological & pharmaceutical bulletin},
  year={2003},
  volume={26 4},
  pages={409-16}
}
The actin-binding protein p57, a member of the coronin protein family, is expressed in a variety of immune cells. It has five WD repeats and a coiled-coil motif containing a leucine zipper, both of which are known to mediate protein-protein interactions. In order to identify the precise actin-binding regions in p57, and to assess the contribution of these structural motifs, we prepared various truncated p57 as fusion proteins with glutathione S-transferase (GST) and examined their actin-binding… CONTINUE READING
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