Two putative protein-tyrosine kinases identified by application of the polymerase chain reaction.

@article{Wilks1989TwoPP,
  title={Two putative protein-tyrosine kinases identified by application of the polymerase chain reaction.},
  author={Andrew F. Wilks},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1989},
  volume={86 5},
  pages={1603-7}
}
  • Andrew F. Wilks
  • Published 1989 in
    Proceedings of the National Academy of Sciences…
The pivotal role that protein-tyrosine kinases (PTKs) play in the growth regulation of eukaryotic cells is manifest in the frequent appearance of members of the PTK family as growth factor receptors or as the transforming agents of acutely transforming retroviruses. A feature common to all members of the PTK family is a highly conserved catalytic domain which is characteristic of the group as a whole and whose activity appears to be tightly regulated within the cell by other domains of the PTK… CONTINUE READING
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