Two polyketide synthase-encoding genes are required for biosynthesis of the polyketide virulence factor, T-toxin, by Cochliobolus heterostrophus.

@article{Baker2006TwoPS,
  title={Two polyketide synthase-encoding genes are required for biosynthesis of the polyketide virulence factor, T-toxin, by Cochliobolus heterostrophus.},
  author={Scott E Baker and Scott Kroken and Patrik Inderbitzin and Thipa Asvarak and Bi-Yu Li and Liang Shi and Olen C. Yoder and B Gillian Turgeon},
  journal={Molecular plant-microbe interactions : MPMI},
  year={2006},
  volume={19 2},
  pages={
          139-49
        }
}
Cochliobolus heterostrophus race T, causal agent of southern corn leaf blight, requires T-toxin (a family of C35 to C49 polyketides) for high virulence on T-cytoplasm maize. Production of T-toxin is controlled by two unlinked loci, Tox1A and Tox1B, carried on 1.2 Mb of DNA not found in race O, a mildly virulent form of the fungus that does not produce T-toxin, or in any other Cochliobolus spp. or closely related fungus. PKS1, a polyketide synthase (PKS)-encoding gene at Tox1A, and DEC1, a… CONTINUE READING

Similar Papers

Citations

Publications citing this paper.
SHOWING 1-10 OF 52 CITATIONS, ESTIMATED 83% COVERAGE

Horizontal gene and chromosome transfer in plant pathogenic fungi affecting host range.

  • FEMS microbiology reviews
  • 2011
VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

FILTER CITATIONS BY YEAR

2006
2019

CITATION STATISTICS

  • 11 Highly Influenced Citations

References

Publications referenced by this paper.
SHOWING 1-10 OF 35 REFERENCES

Structure of the host - specific pathotoxins produced by Phyllosticta maydis

S. Kroken, N. L. Glass, J. W. Taylor, O. C. Yoder, B. G. Turgeon
  • Tetrahedron Lett .
  • 2003
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

Electrophoretic confirmation of chromosome rearrangements in Cochliobolus heterostrophus : Translocation at Tox 1

T. Tzeng, H. Chang, C. R. Bronson
  • Phytopathology
  • 1989
VIEW 2 EXCERPTS
HIGHLY INFLUENTIAL

Tagged mutations at the Tox 1 locus of Cochliobolus het - erostrophus using restriction enzyme - mediated integration

D. M. Mukunya, C. W. Boothroyd
  • Proc . Natl . Acad . Sci . U . S . A .
  • 1973
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL