Two piperazic acid-containing cyclic hexapeptides from Streptomyces alboflavus 313

@article{Wei2012TwoPA,
  title={Two piperazic acid-containing cyclic hexapeptides from Streptomyces alboflavus 313},
  author={Shaopeng Wei and Lixia Fan and Wenjun Wu and Zhiqin Ji},
  journal={Amino Acids},
  year={2012},
  volume={43},
  pages={2191-2198}
}
Two novel cyclic hexapeptides, designated NW-G10 (1) and NW-G11 (2), were isolated from the fermentation broth of Streptomyces alboflavus 313. Their relative structures were elucidated on the basis of extensive spectroscopic analysis, and the absolute configurations of several constituent amino acids were determined by Marfey’s method. NW-G10 (1) and NW-G11 (2) exhibited significant activity against Gram-positive bacteria, such as Bacillus cereus, Bacillus subtilis and Staphylococcus aureus… CONTINUE READING