Two-photon vibrational spectroscopy for biosciences based on surface-enhanced hyper-Raman scattering.

@article{Kneipp2006TwophotonVS,
  title={Two-photon vibrational spectroscopy for biosciences based on surface-enhanced hyper-Raman scattering.},
  author={Janina Kneipp and Harald Kneipp and Katrin Kneipp},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2006},
  volume={103 46},
  pages={17149-53}
}
Two-photon excitation is gaining rapidly in interest and significance in spectroscopy and microscopy. Here we introduce a new approach that suggests versatile optical labels suitable for both one- and two-photon excitation and also two-photon-excited ultrasensitive, nondestructive chemical probing. The underlying spectroscopic effect is the incoherent inelastic scattering of two photons on the vibrational quantum states called hyper-Raman scattering (HRS). The rather weak effect can be… CONTINUE READING