Two-photon imaging of chronically implanted neural electrodes: Sealing methods and new insights.


BACKGROUND Two-photon microscopy has enabled the visualization of dynamic tissue changes to injury and disease in vivo. While this technique has provided powerful new information, in vivo two-photon chronic imaging around tethered cortical implants, such as microelectrodes or neural probes, present unique challenges. NEW METHOD A number of strategies are… (More)
DOI: 10.1016/j.jneumeth.2015.10.007


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